Prospective study of ALDH1A1 gene polymorphisms associated with antituberculosis drug‐induced liver injury in western Chinese Han population

association of interleukin 18 gene promoter polymorphisms with hbv recurrence after liver transplantation in han chinese population

ACYP2 polymorphisms are associated with the risk of liver cancer in a Han Chinese population

We explored the association between single nucleotide polymorphisms (SNPs) in ACYP2 and liver cancer risk. Thirteen SNPs were genotyped in 473 cases and 564 controls. Genetic model, linkage disequilibrium, and haplotype analyses were performed to evaluate the association between ACPY2 SNPs and liver cancer risk. We found that rs6713088 (G allele: odds ratio [OR] = 1.27, 95% confidence interval ...

Surfactant protein B gene polymorphisms is associated with risk of bronchopulmonary dysplasia in Chinese Han population.

OBJECTIVE To investigate the relationship between Surfactant protein B (SP-B) gene polymorphisms and bronchopulmonary dysplasia (BPD) development in preterm infants of China Han ethnic population. METHODS SP-B gene polymorphisms were studied in 134 neonates who were born at <32 weeks of gestation, with the diagnosis of BPD and in a control group of 168 preterm infants without BPD. Genotyping ...

RAD52 gene polymorphisms are associated with risk of colorectal cancer in a Chinese Han population

Upward trends in the incidence and mortality rates of colorectal cancer (CRC) in China over the past decade mean that it is critical to improve survival outcomes for patients with this malignancy. Analysis of genetic variants may identify biomarkers that have a role in CRC susceptibility and clinical outcomes in Chinese patients with CRC. RAD52 is a key mediator during DNA strand exchange and h...

Polymorphisms in TCF7L2 gene are associated with gestational diabetes mellitus in Chinese Han population

This study aimed to investigate the possible association between diabetes susceptibility gene transcription factor 7-like 2 (TCF7L2) and gestational diabetes mellitus (GDM) in a Chinese Han population. A total of 556 GDM patients and 500 Non-GDM were included. Eighteen single nucleotide polymorphisms (SNPs) were evaluated. Fifteen tag SNPs were selected from HapMap CHB database with a minor all...